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Andrei Corbu

CNRS Research Associate CR1


1, avenue de la Terrasse

91190 Gif-sur-Yvette France

- Education and work experience

2017–présent CNRS research associate at ICSN.

2010–2017 CNRS research associate at ESPCI, UMR 8231 Chimie, Biologie, Innovation, Laboratoire de Chimie Organique, Paris

2009 – 2010 Post-doctoral stint at The Scripps Research Institute, La Jolla, USA, with Prof. K.C. Nicolaou

2005 – 2008 Ph.D. at ICSN/Ecole Polytechnique under the guidance of Dr. Siméon Arseniyadis.

2002 – 2005 Bachelor and master degrees at École Polytechnique, Palaiseau, X2001.

2000 – 2001 Erasmus Scholarship at Universitat Autonoma de Barcelona, Spain.

- Research Interests

Total synthesis of bioactive meroterpenes

Synthetically useful, biocatalyzed transformations

CH activation by enzymes

Original synthetic methods involving iron and palladium catalysis

- Selected recent publications

1. Maiga-Wandiam, B., Corbu, A., Massiot, G., Sautel, F., Yu, P., Lin, B. W.-Y., Houk, K. N., Cossy, J. Intramolecular Diels-Alder approaches to the decalin core of verongidolide. The origin of the exo-selectivity: a DFT analysis. J. Org. Chem, in press

2. Calmus, L.; Corbu, A.; Cossy, J. 2H-Chromenes Generated by an Iron(III) Complex-Catalyzed Allylic Cyclization Adv. Synth. Catal. 2015, 357, 1381–1386

3. Butkevich, A.N.; Meerpoel, L.; Stansfield, I.; Angibaud, P.; Corbu, A.; Cossy, J. Tandem Suzuki-Miyaura Coupling/Acid-Catalyzed Cyclization Between Vinyl Ether Boronates and Vinyl Halides: a Concise Approach to Polysubstituted Furans. Org. Lett., 2013, 15, 3840–3843.

4. Nicolaou, K.C.; Jiang, X.; Lindsay-Scott, P.J.; Corbu, A.; Yamashiro, S.; Bacconi, A.; Fowler, V.M. Total Synthesis and Biological Evaluation of Monorhizopodin and 16-Epi-Monorhizopodin. Angew. Chem. Int. Ed., 2011, 50, 1139–1144.

5. Corbu, A.; Perez, M.; Aquino, M.; Retailleau, P.; Arseniyadis, S. Total Synthesis and Structural Confirmation of Ent-Galbanic Acid and Marneral. Org. Lett., 2008, 10, 2853–2856.

6. Corbu, A.; Aquino, M.; Pratap, T.V.; Retailleau, P.; Arseniyadis, S. Enantioselective Synthesis of Iridal, the Parent Molecule of the Iridal Triterpenoid Class. Org. Lett., 2008, 10, 1787–1790.